The expression of HER-2 in extramammary Paget's disease
نویسندگان
چکیده
منابع مشابه
Evaluation of Expression of EGFR, HER-2 and COX-2 in Colorectal Cancer
Background and objective: EGFR and HER-2 are two members of ERbB/HER family of Type I Transmembrane growth factor receptors. Cox2 is an enzyme responsible for the conversion of arachidonic acid to prostaglandins, which has a major role in angiogenesis and can modelate tumor growth. The aim of this study was to determine the level of expression of EGFR, HER-2 and Cox2 in colorectd cancer. Mater...
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Sir, Extramammary Paget's disease occurs either in the anogenital region, in the axilla, or most commonly in the vulva (1). It occurs more frequently in women than men and usually occurs in the ®fth decade or later. In some cases, an underlying sweat gland adenocarcinoma or a primary carcinoma of other organs, such as the rectum, urethra or cervix uteri is found; however, in other cases it occu...
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AIM OF THE STUDY To determine whether the expression of HER-3 influences the survival of HER-2 positive patients with breast cancer (BC). MATERIAL AND METHODS In the present work, the expression of HER-3 in a group of 35 HER-2 positive patients with BC was studied by performing immunohistochemistry (IHC) in formalin-fixed paraffin embedded tissues. RESULTS Higher HER-3 status if estimated b...
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ژورنال
عنوان ژورنال: BioScience Trends
سال: 2011
ISSN: 1881-7815,1881-7823
DOI: 10.5582/bst.2011.v5.4.151